Protein folding and tRNA biology
نویسندگان
چکیده
منابع مشابه
Protein Stability, Folding, Disaggregation and Etiology of Conformational Malfunctions
Estimation of protein stability is important for many reasons: first providing an understanding of the basic thermodynamics of the process of folding, protein engineering, and protein stability plays important role in biotechnology especially in food and protein drug design. Today, proteins are used in many branches, including industrial processes, pharmaceutical industry, and medical fields. A...
متن کاملComputational Biology Lecture 21: Protein folding and threading
As was the case with RNA folding, the goal is to determine the three-dimensional structure of a protein based on its amino acid sequence. There is a strong belief that the amino acid sequence completely and uniquely determines the folding. This is reinforced by the following experiment: Unfold a protein (by exerting a certain temperature) and then release it such that no other substances are pr...
متن کاملProtein folding: a perspective for biology, medicine and biotechnology.
At the present time, protein folding is an extremely active field of research including aspects of biology, chemistry, biochemistry, computer science and physics. The fundamental principles have practical applications in the exploitation of the advances in genome research, in the understanding of different pathologies and in the design of novel proteins with special functions. Although the deta...
متن کاملPhysical-organic molecular biology: pathway and stability of protein folding
Protein engineering, the design and synthesis of novel proteins by genetic engineering, allows complex problems in molecular biology to be studied by structure-activity relationships in an analogous manner to the application of physical-organic chemistry to simple organic molecules. This approach has been applied to study the folding pathway and stability of barnase, the RNAse from Bacillus amy...
متن کاملtRNA Biology in Mitochondria
Mitochondria are the powerhouses of eukaryotic cells. They are considered as semi-autonomous because they have retained genomes inherited from their prokaryotic ancestor and host fully functional gene expression machineries. These organelles have attracted considerable attention because they combine bacterial-like traits with novel features that evolved in the host cell. Among them, mitochondri...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Reviews
سال: 2017
ISSN: 1867-2450,1867-2469
DOI: 10.1007/s12551-017-0322-2